Identification of Indazole-Based Thiadiazole-Bearing Thiazolidinone Hybrid Derivatives: Theoretical and Computational Approaches to Develop Promising Anti-Alzheimer's Candidates

• Main Authors: Yousaf Khan (Author), Shoaib Khan (Author), Rafaqat Hussain (Author), Wajid Rehman (Author), Aneela Maalik (Author), Urooba Gulshan (Author), Mohamed W. Attwa (Author), Hany W. Darwish (Author), Hazem A. Ghabbour (Author), Nawab Ali (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A hybrid library of compounds based on indazole-based thiadiazole containing thiazolidinone moieties (<b>1</b>-<b>17</b>) was synthesized. The synthesized compounds were screened in vitro for their inhibition profile against targetedacetylcholinesterase (AChE) and butyrylchol...