A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E ε4 allele

• Main Authors: Gleason Carey E (Author), Meethal Sivan (Author), Ahmadi M Reza (Author), Haasl Ryan J (Author), Johnson Sterling C (Author), Asthana Sanjay (Author), Bowen Richard L (Author), Atwood Craig S (Author)
• Format: Book
• Published: BMC, 2008-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Genetic and biochemical studies support the apolipoprotein E (<it>APOE</it>) ε4 allele as a major risk factor for late-onset Alzheimer's disease (AD), though ~50% of AD patients do not carry the allele. APOE transports cholesterol for luteinizing...