Regulation of Schistosoma mansoni development and reproduction by the mitogen-activated protein kinase signaling pathway.

• Main Authors: Luiza Freire de Andrade (Author), Marina de Moraes Mourão (Author), Juliana Assis Geraldo (Author), Fernanda Sales Coelho (Author), Larissa Lopes Silva (Author), Renata Heisler Neves (Author), Angela Volpini (Author), José Roberto Machado-Silva (Author), Neusa Araujo (Author), Rafael Nacif-Pimenta (Author), Conor R Caffrey (Author), Guilherme Oliveira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Protein kinases are proven targets for drug development with an increasing number of eukaryotic Protein Kinase (ePK) inhibitors now approved as drugs. Mitogen-activated protein kinase (MAPK) family members connect cell-surface receptors to regulatory targets within cells and influence a n...