Combination of Sildenafil and Ba2+ at a Low Concentration Show a Significant Synergistic Inhibition of Inward Rectifier Potassium Current Resulting in Action Potential Prolongation

Sildenafil (Viagra) is a vasodilator mainly used in the treatment of erectile dysfunction. Atrial or ventricular fibrillation may rarely occur as a side effect during sildenafil therapy. Although changes in inward rectifier potassium currents including IK1 are known to contribute to the pathogenesis...

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Main Authors: Martin Macháček (Author), Olga Švecová (Author), Markéta Bébarová (Author)
Format: Book
Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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