3D-QSAR modeling and pharmacophore study of serotonin 5HT-₂A receptors antagonists

• Main Authors: Antonijević Mirjana (Author), Nikolić Katarina (Author), Vučićević Jelica (Author), Oljačić Slavica (Author), Agbaba Danica (Author)
• Format: Book
• Published: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Creation of a statistically reliable 3D-QSAR (Quantitative Structure Activity Relationships) model enables definition of the structure of the pharmacophore for antagonists of serotonin 5-HT2A receptors and selection of the key molecular determinants for the design of new antagonists. A 3D-QSAR study...