Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome

Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome

Seckel syndrome is a type of microcephalic primordial dwarfism (MPD) that is characterized by growth retardation and neurodevelopmental defects, including reports of retinopathy. Mutations in key mediators of the replication stress response, the mutually dependent partners ATR and ATRIP, are among t...

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Main Authors: Gabriel E. Matos-Rodrigues (Author), Pedro B. Tan (Author), Maurício Rocha-Martins (Author), Clara F. Charlier (Author), Anielle L. Gomes (Author), Felipe Cabral-Miranda (Author), Paulius Grigaravicius (Author), Thomas G. Hofmann (Author), Pierre-Olivier Frappart (Author), Rodrigo A. P. Martins (Author)
Format: Book
Published: The Company of Biologists, 2020-10-01T00:00:00Z.
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