A Novel EphA2 Inhibitor Exerts Beneficial Effects in PI-IBS in Vivo and in Vitro Models via Nrf2 and NF-κB Signaling Pathways

• Главные авторы: Li Zeng (Автор), Kaixue Li (Автор), Hong Wei (Автор), Jingjing Hu (Автор), Lu Jiao (Автор), Shaoyong Yu (Автор), Ying Xiong (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Though the detailed pathological mechanism of post-infectious irritable bowel syndrome (PI-IBS) remains unclear, accumulating evidence indicates that oxidative stress and inflammation are implicated in the process of PI-IBS. Oxidative stress and inflammation are regulated by Nrf2 and NF-κB signaling...