Gram-Negative Bacteria Salmonella typhimurium Boost Leukotriene Synthesis Induced by Chemoattractant fMLP to Stimulate Neutrophil Swarming

• Main Authors: Ekaterina A. Golenkina (Author), Svetlana I. Galkina (Author), Olga Pletjushkina (Author), Boris Chernyak (Author), Tatjana V. Gaponova (Author), Yulia M. Romanova (Author), Galina F. Sud'ina (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leukotriene synthesis in neutrophils is critical for host survival during infection. In particular, leukotriene B4 (LTB4) is a powerful neutrophil chemoattractant that plays a crucial role in neutrophil swarming. In this work, we demonstrated that preincubation of human neutrophils with Salmonella t...