Emodin alleviates cardiac fibrosis by suppressing activation of cardiac fibroblasts via upregulating metastasis associated protein 3

• Main Authors: Dan Xiao (Author), Yue Zhang (Author), Rui Wang (Author), Yujie Fu (Author), Tong Zhou (Author), Hongtao Diao (Author), Zhixia Wang (Author), Yuan Lin (Author), Zhange Li (Author), Lin Wen (Author), Xujuan Kang (Author), Philipp Kopylov (Author), Dmitri Shchekochikhin (Author), Yong Zhang (Author), Baofeng Yang (Author)
• Format: Book
• Published: Elsevier, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Excess activation of cardiac fibroblasts inevitably induces cardiac fibrosis. Emodin has been used as a natural medicine against several chronic diseases. The objective of this study is to determine the effects of emodin on cardiac fibrosis and the underlying molecular mechanisms. Intragastric admin...