Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase from Trichomonas vaginalis

• Main Authors: Linda J. Urbański (Author), Anna Di Fiore (Author), Latifeh Azizi (Author), Vesa P. Hytönen (Author), Marianne Kuuslahti (Author), Martina Buonanno (Author), Simona M. Monti (Author), Andrea Angeli (Author), Reza Zolfaghari Emameh (Author), Claudiu T. Supuran (Author), Giuseppina De Simone (Author), Seppo Parkkila (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We report the biochemical and structural characterisation of a beta-carbonic anhydrase (β-CA) from Trichomonas vaginalis, a unicellular parasite responsible for one of the world's leading sexually transmitted infections, trichomoniasis. CAs are ubiquitous metalloenzymes belonging to eight evolu...