Relationship of plasma 3‐carboxy‐4‐methyl‐5‐propyl‐2‐furanpropanoic acid concentration with OATP1B activity in patients with chronic kidney disease

• Main Authors: Hiroyuki Ono (Author), Ryota Tanaka (Author), Yosuke Suzuki (Author), Ayako Oda (Author), Haruki Sato (Author), Ryosuke Tatsuta (Author), Tadasuke Ando (Author), Toshitaka Shin (Author), Keiko Ohno (Author), Hiroki Itoh (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Organic anion‐transporting polypeptides (OATP)1B are drug transporters mainly expressed in the sinusoidal membrane. Many studies have suggested that OATP1B activity is affected by genetic factor, the uremic toxin 3‐carboxy‐4‐methyl‐5‐propyl‐2‐furanpropanoic acid (CMPF), and inflammatory cyt...