Relationship of plasma 3‐carboxy‐4‐methyl‐5‐propyl‐2‐furanpropanoic acid concentration with OATP1B activity in patients with chronic kidney disease

• Главные авторы: Hiroyuki Ono (Автор), Ryota Tanaka (Автор), Yosuke Suzuki (Автор), Ayako Oda (Автор), Haruki Sato (Автор), Ryosuke Tatsuta (Автор), Tadasuke Ando (Автор), Toshitaka Shin (Автор), Keiko Ohno (Автор), Hiroki Itoh (Автор)
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• Опубликовано: Wiley, 2024-02-01T00:00:00Z.
• Предметы: article
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Abstract Organic anion‐transporting polypeptides (OATP)1B are drug transporters mainly expressed in the sinusoidal membrane. Many studies have suggested that OATP1B activity is affected by genetic factor, the uremic toxin 3‐carboxy‐4‐methyl‐5‐propyl‐2‐furanpropanoic acid (CMPF), and inflammatory cyt...