Pharmacological Inhibition of Gal-3 in Mesenchymal Stem Cells Enhances Their Capacity to Promote Alternative Activation of Macrophages in Dextran Sulphate Sodium-Induced Colitis

Pharmacological Inhibition of Gal-3 in Mesenchymal Stem Cells Enhances Their Capacity to Promote Alternative Activation of Macrophages in Dextran Sulphate Sodium-Induced Colitis

Transplantation of mesenchymal stem cells (MSCs) reduces the severity of dextran sulphate sodium- (DSS-) induced colitis. MSCs are able to secrete Galectin-3 (Gal-3), a protein known to affect proliferation, adhesion, and migration of immune cells. We investigate whether newly synthetized inhibitor...

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Main Authors: Bojana Simovic Markovic (Author), Aleksandar Nikolic (Author), Marina Gazdic (Author), Jasmin Nurkovic (Author), Irena Djordjevic (Author), Nebojsa Arsenijevic (Author), Miodrag Stojkovic (Author), Miodrag L. Lukic (Author), Vladislav Volarevic (Author)
Format: Book
Published: Hindawi Limited, 2016-01-01T00:00:00Z.
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