Tumor necrosis factor-α/interleukin-10 balance in normal and cystic fibrosis children

• Main Authors: Galina V. Shmarina (Author), Alexander L. Pukhalsky (Author), Svetlana N. Kokarovtseva (Author), Daria A. Pukhalskaya (Author), Lidia A. Shabalova (Author), Nikolai I. Kapranov (Author), Natalia J. Kashirskaja (Author)
• Format: Book
• Published: Hindawi Limited, 2001-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The balance between tumor necrosis factor-α (TNF-α) and interleukin-10 (IL-10) is important for immune homeostasis maintenance. Exuberant production of TNF-α contributes to overwhelming inflammatory response and tissue damage. But, commonly, increase in TNF-α is counterbalanced by simult...