Icariin regulates miR-23a-3p-mediated osteogenic differentiation of BMSCs via BMP-2/Smad5/Runx2 and WNT/β-catenin pathways in osteonecrosis of the femoral head

• Main Authors: Xiao-yun Zhang (Author), Hua-nan Li (Author), Feng Chen (Author), Yue-ping Chen (Author), Yuan Chai (Author), Jian-zhao Liao (Author), Bin Gan (Author), Ding-peng Chen (Author), Song Li (Author), Yong-qian Liu (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Icariin is commonly used for the clinical treatment of osteonecrosis of the femoral head (ONFH). miR-23a-3p plays a vital role in regulating the osteogenic differentiation of bone marrow-derived mesenchymal stem cells (BMSCs). The present study aimed to investigate the roles of icariin and miR-23a-3...