Bisdemethoxycurcumin and Its Cyclized Pyrazole Analogue Differentially Disrupt Lipopolysaccharide Signalling in Human Monocyte-Derived Macrophages

• Hoofdauteurs: Serena Tedesco (Auteur), Morena Zusso (Auteur), Laura Facci (Auteur), Annalisa Trenti (Auteur), Carlotta Boscaro (Auteur), Federica Belluti (Auteur), Gian Paolo Fadini (Auteur), Stephen D. Skaper (Auteur), Pietro Giusti (Auteur), Chiara Bolego (Auteur), Andrea Cignarella (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2018-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Several studies suggest that curcumin and related compounds possess antioxidant and anti-inflammatory properties including modulation of lipopolysaccharide- (LPS-) mediated signalling in macrophage cell models. We here investigated the effects of curcumin and the two structurally unrelated analogues...