Screening of important metabolites and KRAS genotypes in colon cancer using secondary ion mass spectrometry

• Main Authors: Kookrae Cho (Author), Eun‐Sook Choi (Author), Sung Young Lee (Author), Jung‐Hee Kim (Author), Dae Won Moon (Author), Jong‐Wuk Son (Author), Eunjoo Kim (Author)
• Format: Book
• Published: Wiley, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Time‐of‐flight secondary ion mass spectrometry (TOF‐SIMS) is an imaging‐based analytical technique that can characterize the surfaces of biomaterials. We used TOF‐SIMS to identify important metabolites and oncogenic KRAS mutation expressed in human colorectal cancer (CRC). We obtained 540 T...