Association Between ABCB1 Polymorphism and Stable Warfarin Dose Requirements in Brazilian Patients

• Main Authors: Letícia C. Tavares (Author), Leiliane R. Marcatto (Author), Renata A. G. Soares (Author), Jose E. Krieger (Author), Alexandre C. Pereira (Author), Paulo C. J. L. Santos (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The ideal dose of the oral anticoagulant warfarin varies widely among patients, mainly due to genetic factors. Genetic variations that impact warfarin pharmacokinetics and the vitamin K cycle are plausible candidates for being associated with warfarin dose requirements. Therefore, the aim of this st...