Newborn Screening for Primary T- and B-Cell Immune Deficiencies-A Prospective Study in Andalucía

• Main Authors: Beatriz de Felipe (Author), Peter Olbrich (Author), Walter Goycochea-Valdivia (Author), Carmen Delgado-Pecellin (Author), Paula Sanchez-Moreno (Author), Berta Sánchez (Author), José Manuel Lucena (Author), Araceli Ferrari-Cortes (Author), Joséfa Salguero Martin de Soto (Author), Josefina Marquez (Author), Carmen Salamanca (Author), Carlos Jimenez Contreras (Author), Olaf Neth (Author)
• Format: Bog
• Udgivet: MDPI AG, 2017-10-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Background: Quantification of T-cell-receptor-excision circles (TRECs) and kappa-deleting-recombination-excision circles (KRECs) from dried blood spots (DBS) allows detection of neonates with severe T-cell and/or B-cell lymphopenia that are potentially affected by severe combined immunodeficiency (S...