Impact of Subacute Exposure to T-2 Toxin and Zearalenone on the Pharmacokinetics of Midazolam as CYP3A Probe Drug in a Porcine Animal Model: A Pilot Study

Cytochrome P450 enzymes (CYP) are important catalyzing proteins involved in the biotransformation of endogenous and xenobiotic compounds. However, their expression and/or activity can be altered by exposure to contaminants such as mycotoxins. In vitro incubations in porcine hepatic microsomes reveal...

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Main Authors: Wim Schelstraete (Author), Mathias Devreese (Author), Siska Croubels (Author)
Format: Book
Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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