Natural compound Alternol exerts a broad anti-cancer spectrum and a superior therapeutic safety index in vivo

• Main Authors: Chenchen He (Author), Linlin Ma (Author), Jeff Hirst (Author), Fei Li (Author), Hao Wu (Author), Wang Liu (Author), Jiang Zhao (Author), Feng Xu (Author), Andrew K. Godwin (Author), Xiangwei Wang (Author), Benyi Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionAlternol is a natural compound isolated from the fermentation of a mutated fungus. We have demonstrated its potent anti-cancer effect via the accumulation of radical oxygen species (ROS) in prostate cancer cells in vitro and in vivo. In this study, we tested its anti-cancer spectrum in m...