The Atrophic Effect of 1,25(OH)₂ Vitamin D₃ (Calcitriol) on C2C12 Myotubes Depends on Oxidative Stress

• Main Authors: Tommaso Raiteri (Author), Ivan Zaggia (Author), Simone Reano (Author), Andrea Scircoli (Author), Laura Salvadori (Author), Flavia Prodam (Author), Nicoletta Filigheddu (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dysfunctional mitochondrial metabolism has been linked to skeletal muscle loss in several physio-pathological states. Although it has been reported that vitamin D (VD) supports cellular redox homeostasis by maintaining normal mitochondrial functions, and VD deficiency often occurs in conditions asso...