The Activity of Aldose Reductase Is Elevated in Diabetic Mouse Heart

• Main Authors: Kazumi Iwata (Author), Toru Nishinaka (Author), Kuniharu Matsuno (Author), Tomoko Kakehi (Author), Masato Katsuyama (Author), Masakazu Ibi (Author), Chihiro Yabe-Nishimura (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The importance of aldose reductase (AR) has been implicated in the pathogenesis of diabetic complications, although the alterations in the expression and activity of AR during hyperglycemia in the heart have not been well characterized. We investigated the expression and enzyme activity of AR in a m...