Klotho supplementation reverses renal dysfunction and interstitial fibrosis in remnant kidney.

• Main Authors: Tsuneo Takenaka (Author), Arif Hasan (Author), Takeshi Marumo (Author), Tsutomu Inoue (Author), Takashi Miyazaki (Author), Hiromichi Suzuki (Author), Yoshifumi Kurosaki (Author), Naohito Ishii (Author), Akira Nishiyama (Author), Matsuhiko Hayashi (Author)
• Format: Book
• Published: Karger Publishers, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: While recent investigations show that klotho exerts reno-protective actions, it has not been fully addressed whether klotho protein supplementation reverses renal damage. Methods: The impacts of subcutaneous klotho supplementation on rats with subtotal nephrectomy were examined. Animal...