Signal transduction of vitamin K3 for pancreas cancer therapy

• Main Authors: Toshiyuki Tanahashi (Author), Shinji Osada (Author), Hisashi Imai (Author), Yoshiyuki Sasaki (Author), Takao Takahashi (Author), Kazuya Yamaguchi (Author), Kazuhiro Yoshida (Author)
• Format: Book
• Published: Frontiers Media S.A., 2011-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We characterized molecular mechanisms of vitamin K3 (VK3)-induced inhibition of proliferation to evaluate VK3 effectiveness in treating advanced pancreatic cancer. A novel endoscopic drug delivery system, ultrasound injection technique, was used to study local effects of VK3. VK3 inhibited pancreas...