Pathogen-specific epitopes as epidemiological tools for defining the magnitude of Mycobacterium leprae transmission in areas endemic for leprosy.

• Main Authors: Marcia V S B Martins (Author), Marjorie M da S Guimarães (Author), John S Spencer (Author), Mariana A V B Hacker (Author), Luciana S Costa (Author), Fernanda M Carvalho (Author), Annemieke Geluk (Author), Jolien J van der Ploeg-van Schip (Author), Maria A A Pontes (Author), Heitor S Gonçalves (Author), Janvier P de Morais (Author), Tereza J P G Bandeira (Author), Maria C V Pessolani (Author), Patrick J Brennan (Author), Geraldo M B Pereira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

During recent years, comparative genomic analysis has allowed the identification of Mycobacterium leprae-specific genes with potential application for the diagnosis of leprosy. In a previous study, 58 synthetic peptides derived from these sequences were tested for their ability to induce production...