The impact of KIR/HLA genes on the risk of developing multibacillary leprosy.

• Main Authors: Hugo Vicentin Alves (Author), Amarilis Giaretta de Moraes (Author), Afonso Carrasco Pepineli (Author), Bruna Tiaki Tiyo (Author), Quirino Alves de Lima Neto (Author), Thais da Silva Santos (Author), Jorge Juarez Vieira Teixeira (Author), Eliane P Ambrosio-Albuquerque (Author), Ana Maria Sell (Author), Jeane Eliete Laguila Visentainer (Author)
• Format: Bog
• Udgivet: Public Library of Science (PLoS), 2019-09-01T00:00:00Z.
• Fag: article
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BACKGROUND:Killer-cell immunoglobulin-like receptors (KIRs) are a group of regulatory molecules able to activate or inhibit natural killer cells upon interaction with human leukocyte antigen (HLA) class I molecules. Combinations of KIR and HLA may contribute to the occurrence of different immunologi...