Soloxolone Methyl Reduces the Stimulatory Effect of Leptin on the Aggressive Phenotype of Murine Neuro2a Neuroblastoma Cells via the MAPK/ERK1/2 Pathway

Soloxolone Methyl Reduces the Stimulatory Effect of Leptin on the Aggressive Phenotype of Murine Neuro2a Neuroblastoma Cells via the MAPK/ERK1/2 Pathway

Despite the proven tumorigenic effect of leptin on epithelial-derived cancers, its impact on the aggressiveness of neural crest-derived cancers, notably neuroblastoma, remains largely unexplored. In our study, for the first time, transcriptome analysis of neuroblastoma tissue demonstrated that the l...

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Main Authors: Kirill V. Odarenko (Author), Oksana V. Salomatina (Author), Ivan V. Chernikov (Author), Nariman F. Salakhutdinov (Author), Marina A. Zenkova (Author), Andrey V. Markov (Author)
Format: Book
Published: MDPI AG, 2023-09-01T00:00:00Z.
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