Soloxolone Methyl Reduces the Stimulatory Effect of Leptin on the Aggressive Phenotype of Murine Neuro2a Neuroblastoma Cells via the MAPK/ERK1/2 Pathway

• 主要な著者: Kirill V. Odarenko (著者), Oksana V. Salomatina (著者), Ivan V. Chernikov (著者), Nariman F. Salakhutdinov (著者), Marina A. Zenkova (著者), Andrey V. Markov (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2023-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Despite the proven tumorigenic effect of leptin on epithelial-derived cancers, its impact on the aggressiveness of neural crest-derived cancers, notably neuroblastoma, remains largely unexplored. In our study, for the first time, transcriptome analysis of neuroblastoma tissue demonstrated that the l...