Ovarian cancer with high-level focal ERBB2 amplification responds to trastuzumab and pertuzumab

• Main Authors: Laure Thouvenin (Author), Mélinda Charrier (Author), Sophie Clement (Author), Yann Christinat (Author), Jean-Christophe Tille (Author), Mauro Frigeri (Author), Krisztian Homicsko (Author), Olivier Michielin (Author), Alexandre Bodmer (Author), Pierre O. Chappuis (Author), Thomas A. McKee (Author), Petros Tsantoulis (Author)
• Format: Book
• Published: Elsevier, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epithelial ovarian cancer (EOC) is usually diagnosed at an advanced stage and significantly contributes to cancer mortality in women. Despite multimodal treatment associating chemotherapy and surgery, most patients ultimately progress and require palliative systemic therapy.In EOC, the efficacy of a...