Membrane Stretch-Induced Activation of a TRPM4-Like Nonselective Cation Channel in Cerebral Artery Myocytes

• Main Authors: Hiromitsu Morita (Author), Akira Honda (Author), Ryuji Inoue (Author), Yushi Ito (Author), Kihachiro Abe (Author), Mark T. Smith (Author), Joseph E. Brayden (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stretch-activated cation channels (SACs) have been observed in many types of smooth muscle cells. However, the molecular identity and activation mechanisms of SACs remain poorly understood. We report that TRPM4-like cation channels are activated by membrane stretch in rat cerebral artery myocytes (C...