Characterization of Hepatitis B Surface Antigen Loaded Polylactic Acid-Based Microneedle and Its Dermal Safety Profile

• Egile Nagusiak: Young-Guk Na (Egilea), Minki Kim (Egilea), Mingu Han (Egilea), Hyun Wook Huh (Egilea), Ji-Seok Kim (Egilea), Jong Chan Kim (Egilea), Jung-Hwan Park (Egilea), Hong-Ki Lee (Egilea), Cheong-Weon Cho (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2020-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

A surge of interest in microneedle (MN) vaccines as a novel vaccination system has emerged. Before the clinical application of MN vaccine, an assessment of potential biological risks to skin and quality control of MN must be performed. Therefore, the present study aims to evaluate the physicochemica...