Evaluation of β-Sitosterol Loaded PLGA and PEG-PLA Nanoparticles for Effective Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and Antitumor Activity

Evaluation of β-Sitosterol Loaded PLGA and PEG-PLA Nanoparticles for Effective Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and Antitumor Activity

β-Sitosterol (β-Sit) is a dietary phytosterol with demonstrated anticancer activity against a panel of cancers, but its poor solubility in water limits its bioavailability and therapeutic efficacy. In this study, poly(lactide-co-glycolic acid) (PLGA) and block copolymers of poly(ethylene glycol)-blo...

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Main Authors: Moses Andima (Author), Gabriella Costabile (Author), Lorenz Isert (Author), Albert J. Ndakala (Author), Solomon Derese (Author), Olivia M. Merkel (Author)
Format: Book
Published: MDPI AG, 2018-11-01T00:00:00Z.
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