Evaluation of β-Sitosterol Loaded PLGA and PEG-PLA Nanoparticles for Effective Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and Antitumor Activity

• Главные авторы: Moses Andima (Автор), Gabriella Costabile (Автор), Lorenz Isert (Автор), Albert J. Ndakala (Автор), Solomon Derese (Автор), Olivia M. Merkel (Автор)
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• Опубликовано: MDPI AG, 2018-11-01T00:00:00Z.
• Предметы: article
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β-Sitosterol (β-Sit) is a dietary phytosterol with demonstrated anticancer activity against a panel of cancers, but its poor solubility in water limits its bioavailability and therapeutic efficacy. In this study, poly(lactide-co-glycolic acid) (PLGA) and block copolymers of poly(ethylene glycol)-blo...