Pipersentan: A De Novo Synthetic Endothelin Receptor Antagonist that Inhibits Monocrotaline- and Hypoxia-Induced Pulmonary Hypertension

• প্রধান লেখক: Zeyu Zhang (লেখক), Chunlei Liu (লেখক), Yongyi Bai (লেখক), Xin Li (লেখক), Xiaojian Gao (লেখক), Chen Li (লেখক), Ge Guo (লেখক), Si Chen (লেখক), Mingzhuang Sun (লেখক), Kang Liu (লেখক), Yang Li (লেখক), Kunlun He (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background: Although major advances have been made in the pathogenesis and management of pulmonary arterial hypertension (PAH), the endothelin system is still considered to play a vital role in the pathology of PAH due to its vasoconstrictive action. Endothelin receptor antagonists (ERAs), either as...