ZhiJingSan Inhibits Osteoclastogenesis via Regulating RANKL/NF-κB Signaling Pathway and Ameliorates Bone Erosion in Collagen-Induced Mouse Arthritis

• Main Authors: Yuanyuan Ling (Author), Jie Yang (Author), Di Hua (Author), Dawei Wang (Author), Chenglei Zhao (Author), Ling Weng (Author), Dandan Yue (Author), Xueting Cai (Author), Qinghai Meng (Author), Jiao Chen (Author), Xiaoyan Sun (Author), Weikang Kong (Author), Lizhong Zhu (Author), Peng Cao (Author), Chunping Hu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bone erosion is the most evident pathological condition of rheumatoid arthritis (RA), which is the main cause of joint deformities and disability in RA patients. At present, the conventional RA drugs have not achieved satisfactory effect in improving bone erosion. ZhiJingSan (ZJS), which is a tradit...