6-Gingerol Regulates Hepatic Cholesterol Metabolism by Up-regulation of LDLR and Cholesterol Efflux-Related Genes in HepG2 Cells

• Main Authors: Xiao Li (Author), Jingting Guo (Author), Ning Liang (Author), Xinwei Jiang (Author), Yuan Song (Author), Shiyi Ou (Author), Yunfeng Hu (Author), Rui Jiao (Author), Weibin Bai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gingerols, the pungent ingredients in ginger, are reported to possess a cholesterol-lowering activity. However, the underlying mechanism remains unclear. The present study was to investigate how 6-gingerol (6-GN), the most abundant gingerol in fresh ginger, regulates hepatic cholesterol metabolism....