Improving anti-tumor activity of sorafenib tosylate by lipid- and polymer-coated nanomatrix

• Main Authors: Yang Guo (Author), Ting Zhong (Author), Xiao-Chuan Duan (Author), Shuang Zhang (Author), Xin Yao (Author), Yi-Fan Yin (Author), Dan Huang (Author), Wei Ren (Author), Qiang Zhang (Author), Xuan Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the present study, we select the Sylysia 350 (Sylysia) as mesoporous material, distearoylphosphatidylethanolamine-poly(ethylene glycol)2000 (DSPE-PEG) as absorption enhancer and hydroxy propyl methyl cellulose (HPMC) as crystallization inhibitor to prepare sorafenib tosylate (SFN) nanomitrix (MSN...