CHIP Haploinsufficiency Exacerbates Hepatic Steatosis via Enhanced TXNIP Expression and Endoplasmic Reticulum Stress Responses

• Hoofdauteurs: Jung-Hwa Han (Auteur), Dae-Hwan Nam (Auteur), Seon-Hui Kim (Auteur), Ae-Rang Hwang (Auteur), So-Young Park (Auteur), Jae Hyang Lim (Auteur), Chang-Hoon Woo (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

TXNIP is a critical regulator of glucose homeostasis, fatty acid synthesis, and cholesterol accumulation in the liver, and it has been reported that metabolic diseases, such as obesity, atherosclerosis, hyperlipidemia, type 2 diabetes, and nonalcoholic fatty liver disease (NAFLD), are associated wit...