Increased Hematopoietic Stem Cells/Hematopoietic Progenitor Cells Measured as Endogenous Spleen Colonies in Radiation-Induced Adaptive Response in Mice (Yonezawa Effect)

• Main Authors: Bing Wang (Author), Kaoru Tanaka (Author), Yasuharu Ninomiya (Author), Kouichi Maruyama (Author), Guillaume Varès (Author), Takanori Katsube (Author), Masahiro Murakami (Author), Cuihua Liu (Author), Akira Fujimori (Author), Kazuko Fujita (Author), Qiang Liu (Author), Kiyomi Eguchi-Kasai (Author), Mitsuru Nenoi (Author)
• Format: Book
• Published: SAGE Publishing, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The existence of radiation-induced adaptive response (AR) was reported in varied biosystems. In mice, the first in vivo AR model was established using X-rays as both the priming and the challenge doses and rescue of bone marrow death as the end point. The underlying mechanism was due to the priming...