The Exposure to Osteoarthritic Synovial Fluid Enhances the Immunomodulatory Profile of Adipose Mesenchymal Stem Cell Secretome

• Main Authors: Adriana Cifù (Author), Rossana Domenis (Author), Massimo Pozzi-Mucelli (Author), Paolo Di Benedetto (Author), Araldo Causero (Author), Massimo Moretti (Author), Marta Stevanato (Author), Cinzia Pistis (Author), Pier Camillo Parodi (Author), Martina Fabris (Author), Francesco Curcio (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. Several clinical studies have proposed the infusion of adipose mesenchymal stem cells (AMSCs) as an alternative therapy for joint diseases with inflammatory components, such as osteoarthritis. Indeed, AMSCs are able to stimulate tissue repair through a paracrine activity and the interacti...