Altered cytoskeletal arrangement in induced pluripotent stem cells and motor neurons from patients with riboflavin transporter deficiency

• Main Authors: Alessia Niceforo (Author), Chiara Marioli (Author), Fiorella Colasuonno (Author), Stefania Petrini (Author), Keith Massey (Author), Marco Tartaglia (Author), Enrico Bertini (Author), Sandra Moreno (Author), Claudia Compagnucci (Author)
• Format: Book
• Published: The Company of Biologists, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The cytoskeletal network plays a crucial role in the differentiation, morphogenesis, function and homeostasis of the nervous tissue, so that alterations in any of its components may lead to neurodegenerative diseases. Riboflavin transporter deficiency (RTD), a childhood-onset disorder characterized...