The EngCP endo α-N-acetylgalactosaminidase is a virulence factor involved in Clostridium perfringens gas gangrene infections

• Main Authors: Jackie K. Cheung (Author), Vicki Adams (Author), Danielle D'Souza (Author), Meagan James (Author), Christopher J. Day (Author), Michael P. Jennings (Author), Dena Lyras (Author), Julian I. Rood (Author)
• Format: Book
• Published: Elsevier, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clostridium perfringens is the causative agent of human clostridial myonecrosis; the major toxins involved in this disease are α-toxin and perfringolysin O. The RevSR two-component regulatory system has been shown to be involved in regulating virulence in a mouse myonecrosis model. Previous microarr...