Low gamma‐butyrobetaine dioxygenase (BBOX1) expression as a prognostic biomarker in patients with clear cell renal cell carcinoma: a machine learning approach

• Main Authors: Kyu‐Shik Kim (Author), Kyoung Min Moon (Author), Kyueng‐Whan Min (Author), Woon Yong Jung (Author), Su‐Jin Shin (Author), Seung Wook Lee (Author), Mi Jung Kwon (Author), Dong‐Hoon Kim (Author), Sukjoong Oh (Author), Yung‐Kyun Noh (Author)
• Format: Book
• Published: Wiley, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Gamma‐butyrobetaine dioxygenase (BBOX1) is a catalyst for the conversion of gamma‐butyrobetaine to l‐carnitine, which is detected in normal renal tubules. The purpose of this study was to analyze the prognosis, immune response, and genetic alterations associated with low BBOX1 expression in...