Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy
Rheumatoid arthritis (RA) is an inflammatory disease that leads to disability; however, existing therapies are still unsatisfactory. Activated fibroblast-like synoviocytes (FLSs) play an essential role in synovitis formation and joint destruction in RA. The Hedgehog signaling pathway is aberrantly a...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2023-03-01T00:00:00Z.
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