Rac1 GTPase Inhibition Blocked Podocyte Injury and Glomerular Sclerosis during Hyperhomocysteinemia via Suppression of Nucleotide-Binding Oligomerization Domain-Like Receptor Containing Pyrin Domain 3 Inflammasome Activation

Elevated homocysteine (Hcy) levels have been shown to activate nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome leading to podocyte dysfunction and glomerular injury. However, it remains unclear how this inflammasome activation in podocytes is a...

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Main Authors: Qinghua Zhang (Author), Sabena M. Conley (Author), Guangbi Li (Author), Xinxu Yuan (Author), Pin-Lan Li (Author)
Format: Book
Published: Karger Publishers, 2019-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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