Investigation of in vitro susceptibility and resistance mechanisms to amikacin among diverse carbapenemase-producing Enterobacteriaceae

• Main Authors: Xiaoyan Wu (Author), Xiaosi Li (Author), Junjie Yu (Author), Chenliang Fan (Author), Mengli Shen (Author), Xiangchen Li (Author)
• Format: Book
• Published: BMC, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective This study aims to assess the in vitro drug susceptibility of various Carbapenemase-Producing Enterobacteriaceae (CPE) genotypes and elucidate the underlying mechanisms of amikacin resistance. Methods A total of 72 unique CPE strains were collected from the Second Hospital of Jiax...