Biosynthesis of rumbrins and inspiration for discovery of HIV inhibitors

• Main Authors: Beifen Zhong (Author), Jun Wan (Author), Changhui Shang (Author), Jiajia Wen (Author), Yujia Wang (Author), Jian Bai (Author), Shan Cen (Author), Youcai Hu (Author)
• Format: Book
• Published: Elsevier, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Investigation on how nature produces natural compounds with chemical and biological diversity at the genetic level offers inspiration for the discovery of new natural products and even their biological targets. The polyketide rumbrin (1) is a lipid peroxide production and calcium accumulation inhibi...