Identification of a potent dual-function inhibitor for hIMPDH isoforms by computer-aided drug discovery approaches

Inosine monophosphate dehydrogenase (IMPDH) is a key enzyme in de novo biosynthesis of purine nucleotides. Due to this important role, it is a great target to drug discovery for a wide range of activities, especially immunosuppressant in heart and kidney transplantation. Both human IMPDH isoforms ar...

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Main Authors: Meysam Yazdani (Author), Javad Zamani (Author), Seyed Safa-Ali Fatemi (Author)
Format: Book
Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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