Identification of a potent dual-function inhibitor for hIMPDH isoforms by computer-aided drug discovery approaches
Inosine monophosphate dehydrogenase (IMPDH) is a key enzyme in de novo biosynthesis of purine nucleotides. Due to this important role, it is a great target to drug discovery for a wide range of activities, especially immunosuppressant in heart and kidney transplantation. Both human IMPDH isoforms ar...
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| Main Authors: | , , |
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| Format: | Book |
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Frontiers Media S.A.,
2022-10-01T00:00:00Z.
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