The IDI1/SREBP2 axis drives intrahepatic cholestasis and is a treatment target of San-Huang-Cai-Zhu formula identified by sequencing and experiments

• Egile Nagusiak: Junbin Yan (Egilea), Yunmeng Nie (Egilea), Zheng Chen (Egilea), Jiaming Yao (Egilea), Shuo Zhang (Egilea), Zhiyun Chen (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

San-Huang-Chai-Zhu formula (SHCZF), originates from Da-Huang-Xiao-Shi decoction (DHXSD) for the treatment of jaundice as recorded in the Chinese traditional Chinese medicine book Jin Gui Yao Lue. In the clinic, SHCZF has been used to treat cholestasis-related liver disease by improving intrahepatic...