Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma.

• Main Authors: Wilson Lim (Author), Youri Melse (Author), Mickey Konings (Author), Hung Phat Duong (Author), Kimberly Eadie (Author), Benoît Laleu (Author), Benjamin Perry (Author), Matthew H Todd (Author), Jean-Robert Ioset (Author), Wendy W J van de Sande (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Eumycetoma is a chronic infectious disease characterized by a large subcutaneous mass, often caused by the fungus Madurella mycetomatis. A combination of surgery and prolonged medication is needed to treat this infection with a success rate of only 30%. There is, therefore, an urgent need to find mo...